The presentation was delivered and recorded during the 10th Lifecourse Prevention Summit 2025

In this briefing, Susanna Esposito reviews the current landscape of pediatric RSV prevention, comparing the available immunization strategies and presenting real-world evidence from Spain, Italy, Luxembourg, the United Kingdom, and other countries. She shows that significant reductions in hospitalizations and ICU admissions have been achieved where high coverage was reached, and examines the trade-offs between different approaches including cost, coverage rates, and the limitations of relying on a single strategy.

Esposito highlights Luxembourg's combined approach as a model that achieved high coverage and a substantial reduction in RSV burden. Her central message is that all infants need protection, and that each country must determine the best strategy based on its healthcare infrastructure, costs, and population attitudes. This session further explores the subject in depth, highlighting key takeaways, implications for policy and practice, and insights from the expert presenter to help inform future strategies.