Mélia La Défense – Paris – Eiffel I+II (19th Floor)
The 10th Lifecourse Prevention Summit convened on 4–5 December 2025, bringing together experts, clinicians, policymakers, and representatives of professional organizations to address critical challenges inimmunization and prevention across every stage of life. The Summit included three working sessions held over two days.
The first meeting, "Lifecourse Prevention,"examined the scientific and policy foundations of healthy aging. Experts addressed definitions and global frameworks for healthy aging, emerging evidence on the modifiability of aging trajectories and the lifecourse determinants of later-life health. The meeting also explored the economic and societal case for investing in prevention, the role of health technology assessment in vaccine policy and why adult immunization is essential in an aging society. Action plan discussions focused on how to embed lifecourse principles across health systems and broader societal sectors, align fiscal priorities with long-term health value, strengthen the use of longitudinal data in policy and build more equitable, age-inclusive immunization strategies, including making life-course vaccination a foundational component of pandemic preparedness.
The second meeting, "Vaccination Equity," brought together experts in public health, clinical practice, social science and policy to examine why significant inequities in vaccination uptake and protection persist, despite the availability of safe and effective vaccines and longstanding commitments to universal immunization. The meeting interrogated the systemic drivers of inequity, including data blind spots, structural barriers to access, institutional trust, and community decision-making and focused on the policy levers needed to reduce vaccination gaps, rebuild trust where systems have failed and embed equity into new vaccine introduction and delivery systems from the outset.
The third meeting, "Respiratory Infections," addressed the burden of RSV across all age groups, with particular focus on infants and young children. Experts examined the frequently underestimated impact of RSV, the critical interaction between RSV and pneumococcal disease and real-world evidence from national prevention programs across Europe and beyond. The meeting reinforced the case for universal infant protection strategies and examined the health system conditions needed to translate available prevention tools into meaningful population-level impact. Action plan discussions focused on how to move from fragmented programs to an integrated respiratory immunization strategy across the lifespan, how to raise public awareness and build demand for respiratory infection prevention and what policy levers can expand access and reduce pressure on healthcare systems.
As part of the LifeCourse Prevention Initiative's mission to advance prevention across every stage of life, the Summit's discussions and commitments are intended to translate evidence into policy action across healthy aging, immunization and vaccination equity, informing future program design and policy dialogue within the Initiative and beyond.